Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of glomerular platelet-derived growth factor beta-receptor tyrosine phosphorylation in hypertensive rats and its inhibition by calcium channel blocker.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Mar 2002

Zhan Yumei, Kim Shokei, Kawano Hitomi, Iwao Hiroshi

Abstract excerpt

The molecular mechanism of glomerular injury in hypertension remains to be clarified. In this study, to examine the possible role of platelet-derived growth factor (PDGF) receptors in hypertensive glomerular injury, we specifically measured glomerular PDGF receptor tyrosine phosphorylation in various models of hypertensive rats using immunoprecipitation and Western blot analysis. A high-salt diet significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Calcium Channel Blockers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kidney Glomerulus

Share to Proteinuria

Share to Rats, Inbred Dahl

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Share to Receptor, Platelet-Derived Growth Factor beta

Source

Identifiers

PMID: 12047046
DOI: 10.1291/hypres.25.295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of glomerular platelet-derived growth factor beta-receptor tyrosine phosphorylation in hypertensive rats and its inhibition by calcium channel blocker.PMID 12047046Read ↗

Transforming growth factor-beta 1 expression and phenotypic modulation in the kidney of hypertensive rats.Semantic proximity Read ↗

Thromboxane A2 Receptor Antagonist (ONO-8809) Attenuates the Renal Disorders Caused by Salt-Overload in Stroke-Prone Spontaneously Hypertensive RatsSemantic proximity Read ↗

Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy.Semantic proximity Read ↗

Hypophosphatemia-mediated hypotension in transgenic mice overexpressing human FGF-23.Semantic proximity Read ↗

Hypertensive glomerular damage as revealed by the expression of alpha-smooth muscle actin and non-muscle myosin.Semantic proximity Read ↗

Angiotensin II receptor blockade limits kidney injury in two-kidney, one-clip Goldblatt hypertensive rats with special reference to phenotypic changes.Semantic proximity Read ↗

Electroporation-mediated PDGF receptor-IgG chimera gene transfer ameliorates experimental glomerulonephritis.Semantic proximity Read ↗

Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.Semantic proximity Read ↗

Activation of dopamine D(1)-like receptor causes phosphorylation of alpha(1)-subunit of Na(+),K(+)-ATPase in rat renal proximal tubules.Semantic proximity Read ↗

Tyr740 and Tyr751 residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor.Semantic proximity Read ↗

Growth-dependent induction of angiotensin II type 2 receptor in rat mesangial cells.Semantic proximity Read ↗

Angiotensin II and calcium blockers prevent glomerular phenotypic changes in remnant kidney model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.