Article
Hypertensive glomerular damage as revealed by the expression of alpha-smooth muscle actin and non-muscle myosin.
Kidney international. Supplement - 1 Jun 1996
Kimura K, Suzuki N, Ohba S, Nagai R, Hiroi J, Mise N, Tojo A, Nagaoka A, Hirata Y, Goto A, Yazaki Y, Omata M
Abstract excerpt
The aim of this study was to determine the phenotypic modulation in mesangial cells of glomeruli damaged by hypertension. Salt-loaded stroke-prone spontaneously hypertensive rats were untreated or treated with a calcium antagonist, manidipine (2 mg/kg/day) for eight weeks. In normotensive Wistar-...
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