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Article

TEL/AML1-positive pediatric leukemia: prognostic significance and therapeutic approaches

1 Jul 2002

Abstract excerpt

This article presents the most recent insights into the biology, prognostic significance, and therapeutic approaches to TEL/AML1-positive leukemia. The TEL/AML1 fusion gene, also known as ETV6 /CBFA2, is the most commonly occurring gene rearrangement in pediatric acute lymphoblastic leukemia (ALL). Considerable controversy exists over its prognostic significance with currently available therapies. Differences in...

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PMID: 12042710
DOI: 10.1097/00062752-200207000-00013

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