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Article

TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance.

1 Mar 1997

Abstract excerpt

PURPOSE: TEL gene rearrangements due to the 12;21 chromosomal translocation are the most common molecular genetic abnormality in childhood acute lymphoblastic leukemia (ALL), occurring in approximately 25% of cases with a B-precursor immunophenotype. The limited number of clinically useful genetic markers in this leukemia subtype prompted us to assess TEL status as a predictor of treatment outcome. PATIENTS AND...

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Identifiers

PMID: 9060558
DOI: 10.1200/jco.1997.15.3.1150

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