Article
Molecular characterization of the genes encoding DNA gyrase and topoisomerase IV of Listeria monocytogenes.
The Journal of antimicrobial chemotherapy - 1 Jun 2002
Lampidis Robert, Kostrewa Dirk, Hof Herbert
Abstract excerpt
The genes encoding subunits A and B of DNA gyrase and subunits C and E of topoisomerase IV of Listeria monocytogenes, gyrA, gyrB, parC and parE, respectively, were cloned and sequenced. Compared with the sequences of quinolone-susceptible bacteria, such as Escherichia coli and Bacillus subtilis, the quinolone resistance-determining region (QRDR) of DNA gyrase subunit A was altered; the deduced amino acid...
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