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Article

Sequence analysis of the gyrA and parC homologues of a wild-type strain of Vibrio parahaemolyticus and its fluoroquinolone-resistant mutants.

Antimicrobial agents and chemotherapy - 1 May 1999

Okuda J, Hayakawa E, Nishibuchi M, Nishino T

Abstract excerpt

Vibrio parahaemolyticus causes seafood-borne gastroenteritis in humans. It is particularly important in Japan, where raw seafood is frequently consumed. Fluoroquinolone is one of the current drugs of choice for treating patients infected by V. parahaemolyticus because resistant strains are rarely found. To study a possible fluoroquinolone resistance mechanism in this organism, nucleotide sequences that are...

Topics

Amino Acid Sequence
Anti-Infective Agents
DNA Gyrase
DNA Topoisomerase IV
DNA Topoisomerases, Type II
Drug Resistance, Microbial
Fluoroquinolones
Gene Expression Regulation, Bacterial
Genes, Bacterial
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Sequence Analysis

Vibrio parahaemolyticus

Source

Open in PubMed Open full text

Identifiers

PMID: 10223929
DOI: 10.1128/AAC.43.5.1156
PMCID: PMC89126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10223929-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Sequence analysis of the gyrA and parC homologues of a wild-type strain of Vibrio parahaemolyticus and its fluoroquinolone-resistant mutants.PMID 10223929Read ↗

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