Article
Association of vitamin D receptor gene 3'-variants with Hashimoto's thyroiditis in the Croatian population.
International journal of immunogenetics - 1 Apr 2008
Stefanić M, Papić S, Suver M, Glavas-Obrovac L, Karner I
Abstract excerpt
Hashimoto's thyroiditis (HT) is the most frequent autoimmune thyroid disease with strong genetic background. Vitamin D receptor (VDR) endocrine system affects immunosuppressive, regulatory and tolerogenic decisions required for induction and maintenance of peripheral immune tolerance. With respect to the biological function of the VDR and functionally plausible gene-expression data, we sought to test whether...
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