Article
[Evaluation of wild-type estrogen receptor beta and its isoforms: ER-beta/delta 5/6 i ER-beta/delta 6 in endometrial adenocarcinoma].
Ginekologia polska - 1 Sept 2003
Witek Andrzej, Skałba Piotr, Paul Monika, Graniczka Michał, Mazurek Urszula, Chromy Grzegorz, Wilczok Tadeusz
Abstract excerpt
Estrogen target genes play essential role among pathogenetic and prognostic factors of endometrial adenocarcinoma; and among them estrogen receptor genes. Although prevailing estrogen receptor type is ER-alpha in endometrium, transduction of signal carried by estrogens can be also mediate by ER-beta, which biological meaning relies on modulation of ER-alpha transcriptional activity. There is hypothesized that...
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