Article
Internal quality control of PCR-based genotyping methods in research studies and patient diagnostics.
Thrombosis and haemostasis - 1 May 2002
Bladbjerg Else-Marie, Gram Jørgen, Jespersen Jørgen, de Maat Moniek P M
Abstract excerpt
Genetic analyses are increasingly integrated in the clinical laboratory, and internal quality control programmes are needed. We have focused on quality control aspects of selected polymorphism analyses used in thrombosis research. DNA was isolated from EDTA-blood (n = 500) by ammonium acetate precipitation and analysed for 18 polymorphisms by polymerase chain reaction (PCR), i. e. restriction fragment length...
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