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Article

Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice.

Behavior genetics - 1 Mar 2002

Levin Edward D, Christopher N Channelle, Lateef Sohail, Elamir Belal M, Patel Manisha, Liang Li-Ping, Crapo James D

Abstract excerpt

Extracellular superoxide dismutase (EC-SOD) controls the availability of extracellular superoxide and appears to play a role in controlling oxidative stress and intercellular signaling. Whether EC-SOD overexpression would help or hinder neurobehavioral function appears to depend on the age of the individual. In young adult mice, we have found that EC-SOD overexpression can interfere with learning on the...

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Source

Identifiers

PMID: 12036109
DOI: 10.1023/a:1015201823417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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