Article
Molecular manipulations of extracellular superoxide dismutase: functional importance for learning.
Behavior genetics - 1 Sept 1998
Levin E D, Brady T C, Hochrein E C, Oury T D, Jonsson L M, Marklund S L, Crapo J D
Abstract excerpt
Extracellular superoxide dismutase (EC-SOD) controls the availability of extracellular superoxide (O2.-), which is important for a variety of physiological pathways, including the primary means of inactivating nitric oxide (NO). The role of EC-SOD in neurobehavioral function has been until now un...
Topics
- Animals
- Brain
- Extracellular Space
- Female
- Gene Expression Regulation, Enzymologic
- Genotype
- Humans
- Male
- Maze Learning
- Mental Recall
- Mice
- Mice, Knockout
- Mice, Transgenic
- Nitric Oxide Synthase
- Pregnancy
- Retention, Psychology
- Superoxide Dismutase