Article
Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetes.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 May 2002
Walder K, Ziv E, Kalman R, Whitecross K, Shafrir E, Zimmet P, Collier G R
Abstract excerpt
OBJECTIVE: To investigate hypothalamic beacon gene expression at various developmental stages in genetically selected diabetes-resistant and diabetes-prone Psammomys obesus. In addition, effects of dietary energy composition on beacon gene expression were investigated in diabetes-prone P. obesus. METHODS: Hypothalamic beacon gene expression was measured using Taqman fluorogenic PCR in 4-, 8- and 16-week-old...
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