Article
The aryl hydrocarbon receptor nuclear translocator gene polymorphism in patients with recurrent miscarriage.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jan 2006
Sullivan Amy E, Nelson Leesa, Frias Antonio E, Porter T Flint, Branch D Wane, Silver Robert M
Abstract excerpt
OBJECTIVE: The human aryl hydrocarbon receptor nuclear translocator gene (ARNT) is crucial for embryonic development. Knockout of ARNT is embryonic lethal. We thus hypothesized that some cases of recurrent miscarriage (RM) may be due to a polymorphism in the ARNT gene. METHODS: Polymerase chain reaction was used to compare the gene frequencies of a polymorphism in codon 511 of the ARNT gene in 170 women with...
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