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Article

Analysis of cosegregation of intragenic DNA sequence variations as markers of maternal cell contamination in prenatal diagnosis of β-thalassemia.

Translational research : the journal of laboratory and clinical medicine - 1 Mar 2011

Saadi Abdul V, Girisha Katta M, Gopinath Puthiya M, Satyamoorthy Kapaettu

Abstract excerpt

Prenatal diagnosis of 3 HBB gene mutations causing β-thalassemia and hemoglobin D Punjab segregated in a South Indian nuclear family is reported along with a method identified as control for maternal cell contamination (MCC). Amplicons of the HBB gene from genomic DNA obtained from the blood of a thalassemic first child (proband), both parents, and a chorionic villus sample of their second pregnancy were directly...

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Source

Identifiers

PMID: 21316031
DOI: 10.1016/j.trsl.2010.12.005

Genes

MCC
HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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