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Article

Replication fork reversal in DNA polymerase III mutants of Escherichia coli: a role for the beta clamp.

Molecular microbiology - 1 Jun 2002

Grompone Gianfranco, Seigneur Marie, Ehrlich S Dusko, Michel Bénédicte

Abstract excerpt

Certain replication mutations lead in Escherichia coli to a specific reaction named replication fork reversal: at blocked forks, annealing of the nascent strands and pairing of the template strands form a four-way junction. RuvABC-catalysed resolution of this Holliday junction causes chromosome double-strand breaks (DSBs) in a recBC context and therefore creates a requirement for the recombination proteins RecBC...

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Identifiers

PMID: 12028381
DOI: 10.1046/j.1365-2958.2002.02962.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Replication fork reversal in DNA polymerase III mutants of Escherichia coli: a role for the beta clamp.PMID 12028381Read ↗

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