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Article

A fork-clearing role for UvrD.

Molecular microbiology - 1 Sept 2005

Florés Maria-José, Sanchez Nicolas, Michel Bénédicte

Abstract excerpt

The inactivation of a replication protein causes the disassembly of the replication machinery and creates a need for replication reactivation. In several replication mutants, restart occurs after the fork has been isomerized into a four-armed junction, a reaction called replication fork reversal. The repair helicase UvrD is essential for replication fork reversal upon inactivation of the polymerase (DnaE) or the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16135232
DOI: 10.1111/j.1365-2958.2005.04753.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A fork-clearing role for UvrD.PMID 16135232Read ↗

Replication fork reversal in DNA polymerase III mutants of Escherichia coli: a role for the beta clamp.Semantic proximity Read ↗

The DNA repair helicase UvrD is essential for replication fork reversal in replication mutants.Semantic proximity Read ↗

RuvAB is essential for replication forks reversal in certain replication mutants.Semantic proximity Read ↗

UvrD controls the access of recombination proteins to blocked replication forks.Semantic proximity Read ↗

UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR in a rep mutant of Escherichia coli.Semantic proximity Read ↗

The Escherichia coli UvrD helicase is essential for Tus removal during recombination-dependent replication restart from Ter sites.Semantic proximity Read ↗

Robust linear DNA degradation supports replication-initiation-defective mutants in Escherichia coli.Semantic proximity Read ↗

Replication fork collapse at a protein-DNA roadblock leads to fork reversal, promoted by the RecQ helicaseSemantic proximity Read ↗

RuvABC-dependent double-strand breaks in dnaBts mutants require recA.Semantic proximity Read ↗

Replication fork reversal after replication-transcription collision.Semantic proximity Read ↗

UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.Semantic proximity Read ↗

The RdgC protein of Escherichia coli binds DNA and counters a toxic effect of RecFOR in strains lacking the replication restart protein PriA.Semantic proximity Read ↗

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