Article
Saccharomyces cerevisiae RNA polymerase II is affected by Kluyveromyces lactis zymocin.
The Journal of biological chemistry - 19 Jul 2002
Jablonowski Daniel, Schaffrath Raffael
Abstract excerpt
The G(1) arrest imposed by Kluyveromyces lactis zymocin on Saccharomyces cerevisiae cells requires a functional RNA polymerase II (pol II) Elongator complex. In studying a link between zymocin and pol II, progressively truncating the carboxyl-terminal domain (CTD) of pol II was found to result in zymocin hypersensitivity as did mutations in four different CTD kinase genes. Consistent with the notion that...
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