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Article

The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

Development (Cambridge, England) - 1 Jun 2002

Katz Jonathan P, Perreault Nathalie, Goldstein Bree G, Lee Catherine S, Labosky Patricia A, Yang Vincent W, Kaestner Klaus H

Abstract excerpt

Klf4 (formerly GKLF) is a zinc-finger transcription factor expressed in the epithelia of the skin, lungs, gastrointestinal tract and several other organs. In vitro studies have suggested that Klf4 plays an important role in cell proliferation and/or differentiation. Mice homozygous for a null mut...

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Source

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Identifiers

PMID: 12015290
DOI: 10.1242/dev.129.11.2619
PMCID: PMC2225535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12015290-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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