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Article

EGFR-dependent network interactions that pattern Drosophila eggshell appendages.

Development (Cambridge, England) - 1 Aug 2012

Simakov David S A, Cheung Lily S, Pismen Len M, Shvartsman Stanislav Y

Abstract excerpt

Similar to other organisms, Drosophila uses its Epidermal Growth Factor Receptor (EGFR) multiple times throughout development. One crucial EGFR-dependent event is patterning of the follicular epithelium during oogenesis. In addition to providing inductive cues necessary for body axes specification, patterning of the follicle cells initiates the formation of two respiratory eggshell appendages. Each appendage is...

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Identifiers

PMID: 22782725
DOI: 10.1242/dev.077669

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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