Article
A discrete model of Drosophila eggshell patterning reveals cell-autonomous and juxtacrine effects.
PLoS computational biology - 1 Mar 2014
Fauré Adrien, Vreede Barbara M I, Sucena Elio, Chaouiya Claudine
Abstract excerpt
The Drosophila eggshell constitutes a remarkable system for the study of epithelial patterning, both experimentally and through computational modeling. Dorsal eggshell appendages arise from specific regions in the anterior follicular epithelium that covers the oocyte: two groups of cells expressing broad (roof cells) bordered by rhomboid expressing cells (floor cells). Despite the large number of genes known to...
Topics
- Animals
- Bone Morphogenetic Proteins
- Computational Biology
- Computer Simulation
- Drosophila melanogaster
- Egg Proteins
- Epidermal Growth Factor
- Epithelium
- Gene Expression Regulation, Developmental
- Gene Regulatory Networks
