Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.

Current biology : CB - 14 May 2002

Strutt David, Johnson Ruth, Cooper Katherine, Bray Sarah

Abstract excerpt

BACKGROUND: During patterning of the Drosophila eye, a critical step is the Notch-mediated cell fate decision that determines the identities of the R3/R4 photoreceptor pair in each ommatidium. Depending on the decision taken, the ommatidium adopts either the dorsal or ventral chiral form. This decision is directed by the activity of the planar polarity genes, and, in particular, higher activity of the receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dishevelled Proteins
Share to Eye
Share to Frizzled Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to JNK Mitogen-Activated Protein Kinases

Share to Mitogen-Activated Protein Kinases

Share to Photoreceptor Cells, Invertebrate

Share to Receptors, Notch

Share to rho GTP-Binding Proteins

Source

Identifiers

PMID: 12015117
DOI: 10.1016/s0960-9822(02)00841-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.PMID 12015117Read ↗

Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye.Semantic proximity Read ↗

frizzled regulates mirror-symmetric pattern formation in the Drosophila eye.Semantic proximity Read ↗

The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye.Semantic proximity Read ↗

Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye.Semantic proximity Read ↗

The role of RhoA in tissue polarity and Frizzled signalling.Semantic proximity Read ↗

Planar cell polarity controls directional Notch signaling in the Drosophila leg.Semantic proximity Read ↗

Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.Semantic proximity Read ↗

Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing.Semantic proximity Read ↗

EGF signaling and ommatidial rotation in the Drosophila eye.Semantic proximity Read ↗

Planar signaling and morphogenesis in Drosophila.Semantic proximity Read ↗

Modeling polarity buildup and cell fate decision in the fly eye: insight into the connection between the PCP and Notch pathways.Semantic proximity Read ↗

Signaling specificity by Frizzled receptors in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.