Article
Planar cell polarity controls directional Notch signaling in the Drosophila leg.
Development (Cambridge, England) - 1 Jul 2012
Capilla Amalia, Johnson Ruth, Daniels Maki, Benavente María, Bray Sarah J, Galindo Máximo Ibo
Abstract excerpt
The generation of functional structures during development requires tight spatial regulation of signaling pathways. Thus, in Drosophila legs, in which Notch pathway activity is required to specify joints, only cells distal to ligand-producing cells are capable of responding. Here, we show that th...
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