Article
C282Y mutation and hepatic iron status in hepatitis C and cryptogenic cirrhosis.
Archives of pathology & laboratory medicine - 1 Nov 2000
Lal P, Fernandes H, Koneru B, Albanese E, Hameed M
Abstract excerpt
BACKGROUND: Increased iron deposition in liver is seen in both primary and secondary hemochromatosis. However, it is not uncommon to see significant iron deposition in a liver biopsy, explant, or autopsy specimen without any significant clinical risk factor. Because of the discovery of the candidate gene (HFE) for hereditary hemochromatosis, we may now be able to screen high-risk patient populations for the...
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