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Article

[The H63D mutation in the HFE gene is related to the risk of hepatocellular carcinoma].

Revista espanola de enfermedades digestivas - 1 Jul 2007

Ropero P, Briceño O, López-Alonso G, Agúndez J A G, González Fernández F A, García-Hoz F, Villegas Martínez A, Díaz-Rubio M, Ladero J M

Abstract excerpt

AIM: To disclose whether mutations in the HFE gene inducing liver iron overload are related to the risk of hepatocellular carcinoma (HCC) in otherwise predisposed patients. PATIENTS AND METHODS: One hundred and ninety-six patients (161 males) diagnosed with HCC and 181 healthy controls were included in the study. All subjects were white Spaniards.C282Y and H63D mutations in the HFE gene were identified in...

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Identifiers

PMID: 17973580
DOI: 10.4321/s1130-01082007000700002

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[The H63D mutation in the HFE gene is related to the risk of hepatocellular carcinoma].PMID 17973580Read ↗

Mutations of the HFE gene in patients with hepatocellular carcinomaSemantic proximity Read ↗

Lack of association between HFE gene mutations and hepatocellular carcinoma in patients with cirrhosis.Semantic proximity Read ↗

Mutations of the HFE gene in patients with hepatocellular carcinomaSemantic proximity Read ↗

HFE gene mutations in alcoholic and virus-related cirrhotic patients with hepatocellular carcinoma.Semantic proximity Read ↗

Mutations in the HFE gene and their interaction with exogenous risk factors in hepatocellular carcinoma.Semantic proximity Read ↗

Incidence of liver disease in people with HFE mutations.Semantic proximity Read ↗

Association of HFE gene C282Y and H63D mutations with liver cirrhosis in the Lithuanian population.Semantic proximity Read ↗

C282Y and H63D mutations of HFE gene in patients with advanced alcoholic liver disease.Semantic proximity Read ↗

Risk of Hepatocellular Carcinoma in Patients with Various HFE Genotypes.Semantic proximity Read ↗

Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma.Semantic proximity Read ↗

Liver iron, HFE gene mutations, and hepatocellular carcinoma occurrence in patients with cirrhosis.Semantic proximity Read ↗

Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.Semantic proximity Read ↗

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