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Article

[The H63D mutation in the HFE gene is related to the risk of hepatocellular carcinoma].

Revista espanola de enfermedades digestivas - 1 Jul 2007

Ropero P, Briceño O, López-Alonso G, Agúndez J A G, González Fernández F A, García-Hoz F, Villegas Martínez A, Díaz-Rubio M, Ladero J M

Abstract excerpt

AIM: To disclose whether mutations in the HFE gene inducing liver iron overload are related to the risk of hepatocellular carcinoma (HCC) in otherwise predisposed patients. PATIENTS AND METHODS: One hundred and ninety-six patients (161 males) diagnosed with HCC and 181 healthy controls were inclu...

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Source

Identifiers

PMID: 17973580
DOI: 10.4321/s1130-01082007000700002

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17973580-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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[The H63D mutation in the HFE gene is related to the risk of hepatocellular carcinoma].PMID 17973580Read ↗

Mutations of the HFE gene in patients with hepatocellular carcinomaSemantic proximity Read ↗

Lack of association between HFE gene mutations and hepatocellular carcinoma in patients with cirrhosis.Semantic proximity Read ↗

Mutations of the HFE gene in patients with hepatocellular carcinomaSemantic proximity Read ↗

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Mutations in the HFE gene and their interaction with exogenous risk factors in hepatocellular carcinoma.Semantic proximity Read ↗

Incidence of liver disease in people with HFE mutations.Semantic proximity Read ↗

Association of HFE gene C282Y and H63D mutations with liver cirrhosis in the Lithuanian population.Semantic proximity Read ↗

C282Y and H63D mutations of HFE gene in patients with advanced alcoholic liver disease.Semantic proximity Read ↗

Risk of Hepatocellular Carcinoma in Patients with Various HFE Genotypes.Semantic proximity Read ↗

Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma.Semantic proximity Read ↗

Liver iron, HFE gene mutations, and hepatocellular carcinoma occurrence in patients with cirrhosis.Semantic proximity Read ↗

Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.Semantic proximity Read ↗

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