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Article

Hemochromatosis gene in leukemia and lymphoma.

Leukemia & lymphoma - 1 Mar 2002

Dorak M Tevfik, Burnett Alan K, Worwood Mark

Abstract excerpt

The gene causing hereditary hemochromatosis (HH), HFE is an HLA class I-like gene with no known immunological function but indirectly related to the immune functions because of its role in iron transport. It is located 6.5 Mb telomeric to HLA-A. The most common mutation of HFE, C282Y, has a Celtic origin and most patients with HH are homozygous for it in Northern European populations. While there is an enormously...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12002748
DOI: 10.1080/10428190290011930

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Hemochromatosis gene in leukemia and lymphoma.PMID 12002748Read ↗

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An extensive analysis of the hereditary hemochromatosis gene HFE and neighboring histone genes: associations with childhood leukemia.Semantic proximity Read ↗

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HFE gene mutation and iron overload in Egyptian pediatric acute lymphoblastic leukemia survivors: a single-center study.Semantic proximity Read ↗

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Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer.Semantic proximity Read ↗

Hereditary hemochromatosis gene (HFE) variants are associated with birth weight and childhood leukemia risk.Semantic proximity Read ↗

Iron transport in a lymphoid cell line with the hemochromatosis C282Y mutation.Semantic proximity Read ↗

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