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Article

Analysis of HFE and TFR2 gene mutations in patients with acute leukemia.

Leukemia research - 1 Jun 2005

Veneri Dino, Franchini Massimo, Krampera Mauro, de Matteis Giovanna, Solero Pietro, Pizzolo Giovanni

Abstract excerpt

There are increasing evidences regarding the association between iron overload and extra-hepatic malignancies. We studied the prevalence of 12 hereditary hemochromatosis (HH) gene mutations (C282Y, V53M, V59M, H63D, H63H, S56C, Q127H, E168Q, E168X, W169X and Q283P in the HFE gene and Y250X in the TFR2 gene) and its correlation with the iron status in 82 adult patients with acute leukemia (AL); 48 patients (58.5%)...

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Source

Identifiers

PMID: 15863206
DOI: 10.1016/j.leukres.2005.01.001

Genes

HFE
TFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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