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Article

Alternative transcripts of presenilin-1 associated with frontotemporal dementia.

Neuroreport - 7 May 2002

Evin Geneviève, Smith Margaret J, Tziotis Angela, McLean Catriona, Canterford Louise, Sharples Robyn A, Cappai Roberto, Weidemann Andreas, Beyreuther Konrad, Cotton Richard G H, Masters Colin L, Culvenor Janetta G

Abstract excerpt

We have analyzed the expression of Alzheimer's disease-associated presenilin 1 (PS1) in various neurodegenerative disorders. Western blotting identified PS1 N- and C-terminal fragments similarly in the cortex of controls, Parkinson, Huntington and schizophrenia subjects. Additional PS1 immunoreactive species of 42 and 46 kDa were present in six out of seven cases of sporadic frontotemporal dementia (FTD) and...

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PMID: 11997713
DOI: 10.1097/00001756-200205070-00036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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