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Article

Expressing mRNAs for presenilin-1 and amyloid precursor protein (APP-695) from same neuronal populations in rat hippocampus.

Brain research bulletin - 1 Jun 1998

Shen Y, Li R

Abstract excerpt

Presenilin-1 gene (PS1, s182) encoding a protein that contains seven transmembrane domains was recently identified as a risk factor for Alzheimer's disease (AD). Mutations on this gene may contribute to pathogenesis of AD. In this study, we used in situ hybridization histochemistry to detect the expression of PS1 in neurons in the hippocampal formation and cerebral cortex of the rat brain. Specifically, mRNAs of...

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Identifiers

PMID: 9667817
DOI: 10.1016/s0361-9230(97)00455-3

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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