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Article

Mutations in the high-affinity IgE receptor beta-chain are not associated with nonresponder status.

Allergy - 1 Aug 2005

Küster H, von Manstein S, Ruocchio-Wiglinghaus S, von Brunn A, Reinhardt D

Abstract excerpt

BACKGROUND: Basophils of some individuals do not release histamine upon activation of their high-affinity immunoglobulin E (IgE) receptor (Fc(epsilon)RI), but do so if this receptor is circumvented for cell activation. This so-called nonresponder phenomenon is clinically relevant, because in various studies atopy was less frequent or absent in nonresponder individuals. So far, it is unknown if this phenomenon is...

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PMID: 15969685
DOI: 10.1111/j.1398-9995.2005.00807.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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