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Article

In vitro selection and characterization of influenza A (A/N9) virus variants resistant to a novel neuraminidase inhibitor, A-315675.

Journal of virology - 1 Jun 2002

Molla Akhteruzzaman, Kati Warren, Carrick Robert, Steffy Kevin, Shi Yan, Montgomery Debra, Gusick Nanette, Stoll Vincent S, Stewart Kent D, Ng Teresa I, Maring Clarence, Kempf Dale J, Kohlbrenner William

Abstract excerpt

With the recent introduction of neuraminidase (NA) inhibitors into clinical practice for the treatment of influenza virus infections, considerable attention has been focused on the potential for resistance development and cross-resistance between different agents from this class. A-315675 is a novel influenza virus NA inhibitor that has potent enzyme activity and is highly active in cell culture against a variety...

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Identifiers

PMID: 11991966
DOI: 10.1128/jvi.76.11.5380-5386.2002
PMCID: PMC137025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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