Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet.

Brain research - 17 May 2002

Gao Jun, Ghibaudi Lorraine, van Heek Margaret, Hwa Joyce J

Abstract excerpt

A subset of Sprague-Dawley rats developed persistent obesity when maintained on a high-fat diet for 6 months followed by a low-fat diet for 1 month, while another subset from the same cohort of rats remained lean on the same diet regimens. The diet-induced obese (DIO) rats had higher energy intake than expenditure, while diet-resistant (DR) rats maintained energy balance. DIO rats also had an increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agouti-Related Protein
Share to Cell Respiration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dietary Fats

Share to Eating

Share to Hypothalamus

Share to Melanins

Share to Neuropeptide Y

Share to Pituitary Hormones

Source

Identifiers

PMID: 11988234
DOI: 10.1016/s0006-8993(02)02493-9

Genes

AGRP
NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet.PMID 11988234Read ↗

Elevated hypothalamic orexin signaling, sensitivity to orexin A, and spontaneous physical activity in obesity-resistant rats.Semantic proximity Read ↗

Hypothalamic neural projections are permanently disrupted in diet-induced obese rats.Semantic proximity Read ↗

F-DIO obesity-prone rat is insulin resistant before obesity onset.Semantic proximity Read ↗

Increased hypothalamic inflammation associated with the susceptibility to obesity in rats exposed to high-fat diet.Semantic proximity Read ↗

Physiological difference between dietary obesity-susceptible and obesity-resistant Sprague Dawley rats in response to moderate high fat diet.Semantic proximity Read ↗

The level of NPY receptor mRNA expression in diet-induced obese and resistant mice.Semantic proximity Read ↗

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset.Semantic proximity Read ↗

Role of fat amount and type in ameliorating diet‐induced obesity: insights at the level of hypothalamic arcuate nucleus leptin receptor, neuropeptide Y and pro‐opiomelanocortin mRNA expressionSemantic proximity Read ↗

Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?Semantic proximity Read ↗

Colony maintenance and the behavioral and physiological characteristics of selectively bred obesity prone and obesity resistant ratsSemantic proximity Read ↗

Differential stress responsivity in diet-induced obese and resistant rats.Semantic proximity Read ↗

Spontaneous physical activity protects against fat mass gain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.