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Article

Mutator clones of Neisseria meningitidis in epidemic serogroup A disease.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Richardson Anthony R, Yu Zhong, Popovic Tanja, Stojiljkovic Igor

Abstract excerpt

Serogroup A Neisseria meningitidis has repeatedly caused widespread epidemics of meningitis and septicemia throughout the 20th century. Recently, in a limited collection of strains, epidemic serogroup A isolates were found to have elevated mutation rates that was caused by defects in mismatch repair pathways. To ascertain the role of these mutators in the epidemic spread of this serogroup, the prevalence of...

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Identifiers

PMID: 11983903
DOI: 10.1073/pnas.092568699
PMCID: PMC122909

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