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Article

Cell adhesion-mediated transformation of a human SCLC cell line is associated with the development of a normal phenotype.

Experimental cell research - 15 May 2002

Gilchrist Anita J, Meuser Renate, Turchinsky Joan, Shaw Andrew R E, Pasdar Manijeh, Dixon Walter T

Abstract excerpt

Small cell lung carcinoma (SCLC) is a highly metastatic disease with a poor prognosis due to its resistance to current modes of therapy. SCLC cells appear to arise by oncogenic transformation of self-renewing pulmonary neuroendocrine cells, which have the potential to differentiate into a variety of lung epithelial cell lineages. Epithelial-mesenchymal conversion involved in such cell type transitions leads to...

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Identifiers

PMID: 11978009
DOI: 10.1006/excr.2002.5502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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