Article
Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer.
Molecular cancer research : MCR - 1 Sept 2010
Ceppi Paolo, Mudduluru Giridhar, Kumarswamy Regalla, Rapa Ida, Scagliotti Giorgio V, Papotti Mauro, Allgayer Heike
Abstract excerpt
The development of metastases is the main reason for cancer-related death in non-small cell lung cancer (NSCLC). The initiation of metastasis involves an increase in cell motility mediated by the loss of cell-cell adhesion caused by E-cadherin repression, in a process commonly known as epithelial...
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