Article
Evolutionary relationships and polymorphisms among V kappa 10 genes from inbred and wild-derived inbred mice.
Immunogenetics - 1 Apr 2002
Fitzsimmons Sean P, Clark Kathleen J, Shapiro Marjorie A
Abstract excerpt
The V kappa 10 family in BALB/c mice is composed of three members, two of which are utilized in a variety of immune responses. We previously demonstrated that the product of the third gene, V kappa 10C, has never been detected as part of a functional antibody and productive rearrangements are selectively lost during B-cell development. Here we analyzed germline V kappa 10 genes from inbred and wild-derived mice...
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