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Article

[Basic approaches to anti-HIV resistance].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 2002

Baba Masanori

Abstract excerpt

Highly active antiretroviral therapy with reverse transcriptase inhibitors(RTIs) and protease inhibitors(PIs) has achieved high-level suppression of viral load in HIV-1-infected patients. However, drug-resistant HIV-1 mutants often emerge, resulting in treatment failure. Various research attempts have been made to overcome the drug-resistance. At present, more than 200 amino acid mutations that confer resistance...

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PMID: 11968785

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Source receipt: pubmed, retrieved 7 Sept 2026.

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