Article
[Human immunodeficiency virus resistance to antiretroviral drugs].
Annales de medecine interne - 1 Dec 1999
Karmochkine M, Descamps D
Abstract excerpt
Antiretroviral compounds can select viral strains presenting mutations of the HIV genome. Certain genotypic modifications are expressed by phenotypic resistance. There is no cross resistance between different classes of compounds (nucleosides, non nucleosides, antiproteases), but cross resistance is common within a given therapeutic class. HIV resistance to antiretroviral compounds is one of the principal causes...
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