Article
[HIV drug resistance].
La Revue du praticien - 15 May 2006
Marcelin Anne-Geneviève, Calvez Vincent
Abstract excerpt
HIV drug resistance can be defined as any change (in protease, reverse transcriptase gene or envelope protein) that improves viral replication in the presence of an inhibitor. One of the most important causes of treatment failure is the development of resistance to antiretrovirals by HIV. Resistance studies have highlighted distinct evolution patterns of mutations and cross resistance among drug classes, which...
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