Article
Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus.
Hepatology (Baltimore, Md.) - 1 Jan 1998
Kuzushita N, Hayashi N, Moribe T, Katayama K, Kanto T, Nakatani S, Kaneshige T, Tatsumi T, Ito A, Mochizuki K, Sasaki Y, Kasahara A, Hori M
Abstract excerpt
The human leukocyte antigen is a crucial genetic factor that initiates or regulates immune response by presenting foreign or self antigens to T lymphocytes. The aim of this study was to investigate whether HLA polymorphism is associated with the onset or progression of liver injury in chronic hepatitis C virus (HCV) infection. We determined HLA class I antigens and class II alleles in 130 hepatitis C virus...
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