Article
Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus.
Hepatology (Baltimore, Md.) - 1 Jan 1998
Kuzushita N, Hayashi N, Moribe T, Katayama K, Kanto T, Nakatani S, Kaneshige T, Tatsumi T, Ito A, Mochizuki K, Sasaki Y, Kasahara A, Hori M
Abstract excerpt
The human leukocyte antigen is a crucial genetic factor that initiates or regulates immune response by presenting foreign or self antigens to T lymphocytes. The aim of this study was to investigate whether HLA polymorphism is associated with the onset or progression of liver injury in chronic hep...
Topics
- Adult
- Alanine Transaminase
- Alleles
- Chronic Disease
- Female
- Gene Frequency
- HLA Antigens
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Haplotypes
- Hepatitis C
- Histocompatibility Antigens Class I
- Humans