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Article

EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos.

Differentiation; research in biological diversity - 1 Mar 2002

Winning Robert S, Ward Emily K, Scales Jon B, Walker Glenn K

Abstract excerpt

The Eph family of receptor tyrosine kinases is involved in limiting cell and tissue interactions via a repulsive mechanism. The mechanism of repulsion involves reorganizing the actin cytoskeleton, but little is known of the molecular components that connect the receptor to the actin cytoskeleton. Recent studies in retinal ganglion cells have demonstrated that EphA4 activates the small GTPase Rho. We have...

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PMID: 11963655
DOI: 10.1046/j.1432-0436.2002.700105.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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