Article
EphrinB2a in the zebrafish retinotectal system.
Journal of neurobiology - 1 Apr 2004
Wagle Mahendra, Grunewald Barbara, Subburaju Sivan, Barzaghi Cristiana, Le Guyader Sylvie, Chan Joanne, Jesuthasan Suresh
Abstract excerpt
Members of the Eph-B family of receptors tyrosine kinase and their transmembrane ligands have been implicated in dorsoventral patterning of the vertebrate retinotectal projection. In the zebrafish retinotectal system, however, ephrinB2a is expressed strongly in the posterior tectum, in tectal neurons that form physical contacts with retinal ganglion cell (RGC) axons. In the gnarled mutant, where tectal neurons...
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