Article
IL1 and TNF gene polymorphisms in patients with juvenile idiopathic arthritis treated with TNF inhibitors.
Annals of the rheumatic diseases - 1 Jul 2007
Cimaz Rolando, Cazalis Marie-Angélique, Reynaud Charlotte, Gerloni Valeria, Zulian Francesco, Biggioggero Martina, Martini Giorgia, Pontikaki Irene, Fantini Flavio, Mougin Bruno, Miossec Pierre
Abstract excerpt
OBJECTIVE: To investigate the genetic contribution of cytokine gene polymorphisms (interleukin 1 (IL1) and tumour necrosis factor alpha (TNFalpha)) on disease phenotype and on response to TNF-blocking agents in a population of patients with juvenile idiopathic arthritis (JIA). METHODS: A cohort o...
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