Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gap junction intercellular communication propagates cell death in cancerous cells.

Oncogene - 27 Mar 2002

Krutovskikh Vladimir A, Piccoli Colette, Yamasaki Hiroshi, Yamasaki Horashi

Abstract excerpt

Gap junction intercellular communication (GJIC) or cell coupling has an important function in maintaining tissue homeostasis and is thus a critical factor in the life and death balance of cells. While the role of GJIC in cell growth regulation has been much studied, its involvement in apoptosis remains unclear. In this study we elucidated the possibility that cell death is propagated via gap junctions, employing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Cell Adhesion
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connexin 43

Share to Gap Junctions

Share to Microscopy, Fluorescence

Share to Tumor Cells, Cultured

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 11960371
DOI: 10.1038/sj.onc.1205187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gap junction intercellular communication propagates cell death in cancerous cells.PMID 11960371Read ↗

Gap junctions and cancer: communicating for 50 years.Semantic proximity Read ↗

Cell-cell communication in carcinogenesis.Semantic proximity Read ↗

Stimulation of intercellular communication of poor-communicating cells by gap-junction-competent cells enhances the HSV-TK/GCV bystander effect in vitro.Semantic proximity Read ↗

Decreased gap-junctional communication associated with segregation of the neuronal phenotype in the RT4 cell-line family.Semantic proximity Read ↗

Defective gap junctional intercellular communication in the carcinogenic process.Semantic proximity Read ↗

Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype.Semantic proximity Read ↗

Dominant-negative connexin43-EGFP inhibits calcium-transient synchronization of primary neonatal rat cardiomyocytes.Semantic proximity Read ↗

Deletion of a single allele of Cx43 is associated with a reduction in the gap junctional intercellular communication and increased cell proliferation of mouse lung pneumocytes type II.Semantic proximity Read ↗

Defective gap junctional intercellular communication in lung cancer: loss of an important mediator of tissue homeostasis and phenotypic regulation.Semantic proximity Read ↗

Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: role of β-catenin/connexin43 association.Semantic proximity Read ↗

Connexins as targets for cancer chemoprevention and chemotherapy.Semantic proximity Read ↗

The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.