Article
rpoB mutation conferring rifampin resistance in Streptococcus pyogenes.
Antimicrobial agents and chemotherapy - 1 May 2002
Aubry-Damon Hélène, Galimand Marc, Gerbaud Guy, Courvalin Patrice
Abstract excerpt
Streptococcus pyogenes BM4478 and Staphylococcus aureus BM4479 were isolated from a patient undergoing rifampin therapy. High-level resistance to rifampin was due to the following mutations in the rpoB gene: Ser522Leu in strain BM4478 and His526Asn and Ser574Leu in strain BM4479.
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