Article
The hOGG1 mutant genotype is associated with prostate cancer susceptibility and aggressive clinicopathological characteristics in the Korean population.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Feb 2012
Yun S J, Ha Y S, Chae Y, Kim J S, Kim I Y, Kim W J
Abstract excerpt
BACKGROUND: The gene encoding human 8-oxoguanine glycosylase 1 (hOGG1) is involved in DNA base excision repair from oxidatively damaged DNA. A case-control study was conducted to evaluate the correlation between the susceptibility and clinicopathological outcomes of prostate cancer (CaP) and hOGG1 genotype. PATIENTS AND METHODS: Subjects were recruited from 266 CaP patients and 266 age-matched benign prostatic...
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