Article
Genetic modeling of estrogen metabolism as a risk factor of hormone-dependent disorders.
Maturitas - 15 Apr 2002
Huber J C, Schneeberger C, Tempfer C B
Abstract excerpt
Estradiol is a pleiotropic hormone, involved in the etiology of a wide variety of diseases. Over the last decade individual genetic variability of the estradiol metabolism has been described as a significant contributor to disease susceptibility with variations depending on ethnic background. Among others, genetic variations of genes encoding cytochrome P450 (CYP) enzymes play an important role in this regard....
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