Article
The Prevalence of Founder Mutations among Individuals from Families with Familial Pancreatic Cancer Syndrome.
Cancer research and treatment - 1 Apr 2017
Lener Marcin R, Kashyap Aniruddh, Kluźniak Wojciech, Cybulski Cezary, Soluch Agnieszka, Pietrzak Sandra, Huzarski Tomasz, Gronwald Jacek, Lubiński Jan
Abstract excerpt
PURPOSE: Familial pancreatic cancer describes families with at least two first-degree relatives with pancreatic cancer that do not fulfil the criteria of other inherited tumor syndromes with increased risks of pancreatic cancer. Although much has been learned regarding the aggregation of pancreatic cancer in some families, the genetic basis for this familial aggregation is poorly understood. This study evaluated...
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