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Article

Heritability of Crohn's disease and ulcerative colitis: a Swedish nationwide population-based twin study.

Journal of Crohn's & colitis - 8 Apr 2026

Grännö Olle, Thunberg Joel, Ludvigsson Jonas F, Kuja-Halkola Ralf, Lindqvist Carl Mårten, Halfvarson Jonas

Abstract excerpt

BACKGROUND AND AIMS: Limited statistical power has hampered previous estimates of concordance between relatives and heritability in inflammatory bowel diseases (IBD). To examine the genetic component of Crohn's disease and ulcerative colitis, we established the largest nationwide IBD twin cohort to date and assessed estimates of concordance and heritability. METHODS: We used the Swedish Twin Registry to identify...

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Identifiers

PMID: 42018767
DOI: 10.1093/ecco-jcc/jjag044
PMCID: PMC13102174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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