Article
Family and twin studies in inflammatory bowel disease.
World journal of gastroenterology - 21 Jun 2006
Halme Leena, Paavola-Sakki Paulina, Turunen Ulla, Lappalainen Maarit, Farkkila Martti, Kontula Kimmo
Abstract excerpt
Studies examining the inheritance of inflammatory bowel disease (IBD) within different family groups have been the basis for recent molecular advances in the genetics of IBD. The derived heritability in Crohn's disease (CD) is higher than in many other complex diseases. The risk of IBD is highest in first-degree relatives of a CD proband, but first-degree relatives of a proband suffering from ulcerative colitis...
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