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Article

Cooperative E‐box regulation of human <i>GLI1</i> by TWIST and USF

18 Mar 2002

Abstract excerpt

Sonic hedgehog signaling plays a critical role in vertebrate patterning, and signaling defects are associated with severe birth defects and cancer in man. GLI1 encodes a critical transcription activator in this pathway. GLI1 is expressed in human basal cell carcinomas and sarcomas. Despite the significance of the GLI1 gene in human disease, few immediate upstream regulators of GLI1 expression are known. We...

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PMID: 11948912
DOI: 10.1002/gene.10078

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Cooperative E‐box regulation of human <i>GLI1</i> by TWIST and USFPMID 11948912Read ↗

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Ultraconserved non‐coding sequence element controls a subset of spatiotemporal GLI3 expressionSemantic proximity Read ↗

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